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Articles (48)
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Rafting through traffic: Membrane domains in cellular logistics

Diaz-Rohrer, Blanca, Levental, Kandice R., Levental, Ilya

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2014

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2014

Modular StarPEG-Heparin Gels with Bifunctional Peptide Linkers

Mikhail V. Tsurkan, Karolina Chwalek, Kandice R. Levental, Uwe Freudenberg, Carsten Werner

Journal:

Macromolecular Rapid Communications

Année:

2010

Langue:

english

Fichier:

PDF, 444 KB

english, 2010

FGF-2 and VEGF functionalization of starPEG–heparin hydrogels to modulate biomolecular and physical cues of angiogenesis

Andrea Zieris, Silvana Prokoph, Kandice R. Levental, Petra B. Welzel, Milauscha Grimmer, Uwe Freudenberg, Carsten Werner

Journal:

Biomaterials

Année:

2010

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2010

Using Mean Field Theory to Guide Biofunctional Materials Design

Uwe Freudenberg, Jens-Uwe Sommer, Kandice R. Levental, Petra B. Welzel, Andrea Zieris, Karolina Chwalek, Katja Schneider, Silvana Prokoph, Marina Prewitz, Ron Dockhorn, Carsten Werner

Journal:

Advanced Functional Materials

Année:

2012

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2012

Two-tier hydrogel degradation to boost endothelial cell morphogenesis

Karolina Chwalek, Kandice R. Levental, Mikhail V. Tsurkan, Andrea Zieris, Uwe Freudenberg, Carsten Werner

Journal:

Biomaterials

Année:

2011

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2011

Sustained delivery of SDF-1α from heparin-based hydrogels to attract circulating pro-angiogenic cells

Silvana Prokoph, Emmanouil Chavakis, Kandice R. Levental, Andrea Zieris, Uwe Freudenberg, Stefanie Dimmeler, Carsten Werner

Journal:

Biomaterials

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Kandice R. Levental, Hongmei Yu, Laura Kass, Johnathon N. Lakins, Mikala Egeblad, Janine T. Erler, Sheri F.T. Fong, Katalin Csiszar, Amato Giaccia, Wolfgang Weninger, Mitsuo Yamauchi, David L. Gasser,

Journal:

Cell

Année:

2009

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2009

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

Mouw, Janna K, Yui, Yoshihiro, Damiano, Laura, Bainer, Russell O, Lakins, Johnathon N, Acerbi, Irene, Ou, Guanqing, Wijekoon, Amanda C, Levental, Kandice R, Gilbert, Penney M, Hwang, E Shelley, Chen,

Journal:

Nature Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2014

Perturbation of Plasma Membrane Physical Properties by Endogenous and Exogenous Mediators Affects Cell Function

Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 120 KB

english, 2014

Structural Determinants of Protein Association with Membrane Rafts and Consequences of Raft Mislocalization

Levental, Ilya, Levental, Kandice, Diaz-Aguilar, Blanca B.

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 41 KB

english, 2014

Differentiation of Plasma Membrane Composition and Physical Properties

Levental, Ilya, Levental, Kandice R.

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 42 KB

english, 2015

[Current Topics in Membranes] Lipid Domains Volume 75 || Giant Plasma Membrane Vesicles: Models for Understanding Membrane Organization

Levental, Kandice R.

Année:

2015

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2015

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

Freudenberg, Uwe, Zieris, Andrea, Chwalek, Karolina, Tsurkan, Mikhail V., Maitz, Manfred F., Atallah, Passant, Levental, Kandice R., Eming, Sabine A., Werner, Carsten

Journal:

Journal of Controlled Release

Année:

2015

Langue:

english

Fichier:

PDF, 2.59 MB

english, 2015

Polyunsaturated Lipids Regulate Membrane Domain Stability by Tuning Membrane Order

Levental, Kandice R., Lorent, Joseph H., Lin, Xubo, Skinkle, Allison D., Surma, Michal A., Stockenbojer, Emily A., Gorfe, Alemayehu A., Levental, Ilya

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2016

Order Differences between Coexisting Liquid Phases Driven by Lipid Unsaturation Determine Phase Separation in Biomimetic Membranes

Lin, Xubo, Lorent, Joseph H., Levental, Kandice R., Gorfe, Alemayehu A., Levental, Ilya

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 36 KB

english, 2016

Dietary Fats Remodel Plasma Membrane Lipidome and Physical Properties to Regulate Phase Separation in Biological Membranes

Levental, Kandice R., Lorent, Joseph H., Lin, Xubo, Gorfe, Alemayehu A., Levental, Ilya

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 40 KB

english, 2016

Structural Determinants of Raft Partitioning for Single-Pass Transmembrane Proteins

Lorent, Joseph H., Diaz-Rohrer, Barbara B., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 39 KB

english, 2016

Defined Polymer-Peptide Conjugates to Form Cell-Instructive starPEG-Heparin Matrices In Situ

Tsurkan, Mikhail V., Chwalek, Karolina, Prokoph, Silvana, Zieris, Andrea, Levental, Kandice R., Freudenberg, Uwe, Werner, Carsten

Journal:

Advanced Materials

Année:

2013

Langue:

english

Fichier:

PDF, 972 KB

english, 2013

Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro

Nowak, Mirko, Freudenberg, Uwe, Tsurkan, Mikhail V., Werner, Carsten, Levental, Kandice R.

Journal:

Biomaterials

Année:

2017

Langue:

english

Fichier:

PDF, 2.48 MB

english, 2017

Domain Stability in Biomimetic Membranes Driven by Lipid Polyunsaturation

Lin, Xubo, Lorent, Joseph Helmuth, Skinkle, Allison D., Levental, Kandice R., Waxham, Melvin Neal, Gorfe, Alemayehu A., Levental, Ilya

Journal:

Journal of Physical Chemistry B

Année:

2016

Langue:

english

Fichier:

PDF, 8.27 MB

english, 2016

Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival

He, Jingquan, Zhang, Feng, Tay, Li Wei Rachel, Boroda, Salome, Nian, Weiqi, Levental, Kandice R., Levental, Ilya, Harris, Thurl E., Chang, Jeffrey T., Du, Guangwei

Journal:

The FASEB Journal

Année:

2017

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2017

Structural determinants and functional consequences of protein affinity for membrane rafts

Lorent, Joseph H., Diaz-Rohrer, Blanca, Lin, Xubo, Spring, Kevin, Gorfe, Alemayehu A., Levental, Kandice R., Levental, Ilya

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2017

n -Alcohol Length Governs Shift in L o - L d Mixing Temperatures in Synthetic and Cell-Derived Membranes

Cornell, Caitlin E., McCarthy, Nicola L.C., Levental, Kandice R., Levental, Ilya, Brooks, Nicholas J., Keller, Sarah L.

Journal:

Biophysical Journal

Année:

2017

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2017

ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis

Levental, Kandice R., Surma, Michal A., Skinkle, Allison D., Lorent, Joseph H., Zhou, Yong, Klose, Christian, Chang, Jeffrey T., Hancock, John F., Levental, Ilya

Journal:

Science Advances

Année:

2017

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2017

Sphingomyelin metabolism is a regulator of KRAS function

van der Hoeven, Dharini, Cho, Kwang-jin, Zhou, Yong, Ma, Xiaoping, Chen, Wei, Naji, Ali, Montufar-Solis, Dina, Zuo, Yan, Kovar, Sarah E., Levental, Kandice R., Frost, Jeffrey A, van der Hoeven, Ransom

Journal:

Molecular and Cellular Biology

Année:

2017

Langue:

english

Fichier:

PDF, 6.45 MB

english, 2017

Author Correction: Structural determinants and functional consequences of protein affinity for membrane rafts

Lorent, Joseph H., Diaz-Rohrer, Blanca, Lin, Xubo, Spring, Kevin, Gorfe, Alemayehu A., Levental, Kandice R., Levental, Ilya

Journal:

Nature Communications

Année:

2018

Langue:

english

Fichier:

PDF, 287 KB

english, 2018

Structural Determinants and Functional Consequences of Protein Association with Membrane Domains

Lorent, Joseph, Diaz-Rohrer, Blanca Barbara, Lin, Xubo, Gorfe, Alex, Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2018

Langue:

english

Fichier:

PDF, 41 KB

english, 2018

Homeostatic Remodeling of Mammalian Membranes in Response to Dietary Lipid Perturbations is Essential for Cellular Fitness

Levental, Kandice R., Malmberg, Eric, Levental, Ilya

Journal:

Biophysical Journal

Année:

2018

Langue:

english

Fichier:

PDF, 39 KB

english, 2018

Tuning Length Scales of Small Domains in Cell-Derived Membranes and Synthetic Model Membranes

Cornell, Caitlin E., Skinkle, Allison D., He, Shushan, Levental, Ilya, Levental, Kandice R., Keller, Sarah L.

Journal:

Biophysical Journal

Année:

2018

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2018

Molecular Mechanism of Microdomain Dependent Protein Trafficking

Diaz-Rohrer, Blanca B., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2018

Langue:

english

Fichier:

PDF, 40 KB

english, 2018

Manipulation of Length Scales in a Modulated Phase in Cell-Derived GPMVs and Synthetic Model GUVs

Cornell, Caitlin E., Skinkle, Allison D., Levental, Ilya, Levental, Kandice R., Keller, Sarah L.

Journal:

Biophysical Journal

Année:

2018

Langue:

english

Fichier:

PDF, 42 KB

english, 2018

Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux

Torres-Adorno, Angie M., Vitrac, Heidi, Qi, Yuan, Tan, Lin, Levental, Kandice R., Fan, Yang-Yi, Yang, Peiying, Chapkin, Robert S., Eckhardt, Bedrich L., Ueno, Naoto T.

Journal:

Oncogene

Année:

2018

Langue:

english

Fichier:

PDF, 4.04 MB

english, 2018

Tuning Length Scales of a Modulated Phase in Model and Cell-Derived Membranes

Cornell, Caitlin E., Skinkle, Allison D., He, Shushan, Levental, Ilya, Levental, Kandice R., Keller, Sarah L.

Journal:

Biophysical Journal

Année:

2019

Langue:

english

Fichier:

PDF, 44 KB

english, 2019

Phase Partitioning of Peptide Anchors in Plasma Membrane Vesicles Predicts Their Recruitment to B Cell Receptor Clusters in Live Cells

Shelby, Sarah A., Serrano, Ivan C., Levental, Kandice R., Levental, Ilya, Veatch, Sarah L.

Journal:

Biophysical Journal

Année:

2019

Langue:

english

Fichier:

PDF, 63 KB

english, 2019

Phosphatidylserine (PS) Externalization Facilitates Membrane Vesiculation through Decreasing Membrane Stiffness

Wang, Hongyin, Lorent, Joseph H., Ganesan, Lakshmi, Diaz-Rohrer, Blanca B., Levental, Kandice R., Malmberg, Eric, Levental, Ilya

Journal:

Biophysical Journal

Année:

2019

Langue:

english

Fichier:

PDF, 40 KB

english, 2019

Phase Partitioning of Peptide Anchors in Plasma Membrane Vesicles Predicts Their Recruitment to B Cell Receptor Clusters in Live Cells

Shelby, Sarah A., Serrano, Ivan C., Levental, Kandice R., Levental, Ilya, Veatch, Sarah L.

Journal:

Biophysical Journal

Année:

2019

Fichier:

PDF, 63 KB

2019

Cell-Derived Plasma Membrane Vesicles Are Permeable to Hydrophilic Macromolecules

Skinkle, Allison D., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 2.98 MB

2020

Phospholipid Translocation as Driver of Cholesterol (Re)Distribution

Doktorova, Milka, Symons, Jessica L., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 49 KB

2020

Simulations of an Asymmetric Mammalian Lipidome

Doktorova, Milka, Levental, Kandice R., Sezgin, Erdinc, Levental, Ilya, Lyman, Edward R.

Journal:

Biophysical Journal

Année:

2020

Langue:

english

Fichier:

PDF, 41 KB

english, 2020

Plasma Membrane Packing Asymmetry Drives Transmembrane Protein Localization

Lorent, Joseph H., Ganesan, Lakshmi, Lyman, Edward R., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Langue:

english

Fichier:

PDF, 40 KB

english, 2020

Lipid Rafts: Controversies Resolved, Mysteries Remain

Levental, Ilya, Levental, Kandice R., Heberle, Frederick A.

Journal:

Trends in Cell Biology

Année:

2020

Langue:

english

Fichier:

PDF, 527 KB

english, 2020

Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness

Levental, Kandice R., Malmberg, Eric, Symons, Jessica L., Fan, Yang-Yi, Chapkin, Robert S., Ernst, Robert, Levental, Ilya

Journal:

Nature Communications

Année:

2020

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2020

Myelin-Associated MAL and PLP Are Unusual Among Multi-Pass Transmembrane Proteins in Preferring Ordered Membrane Domains

CASTELLO-SERRANO, IVAN, Lorent, Joseph Helmuth, Ippolito, Rossana, Levental, Kandice R., Levental, Ilya

Journal:

Journal of Physical Chemistry B

Année:

2020

Fichier:

PDF, 2.71 MB

2020

Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages

Symons, Jessica L., Cho, Kwang-Jin, Chang, Jeffrey T., Du, Guangwei, Waxham, M. Neal, Hancock, John F., Levental, Ilya, Levental, Kandice R.

Journal:

Soft Matter

Année:

2020

Fichier:

PDF, 3.88 MB

2020

Cell-Derived Plasma Membrane Vesicles are Permeable to Hydrophilic Macromolecules

Diaz-Rohrer, Blanca B., Skinkle, Allison, Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 42 KB

2020

Homeoviscous Adaptation in Mammalian Cell Membranes in Response to Dietary Lipid Perturbations is Necessary for Cell Survival

Levental, Kandice R., Symons, Jessica L., Fan, Yang-Yi, Chapkin, Robert, Ernst, Robert, Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 44 KB

2020

Plasma Membrane Permeability is Altered in Living Mammalian Cells by Perturbations of Lipid Membrane Composition

Symons, Jessica L., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 40 KB

2020

Coupling between Cytoplasmic Protein Phase Separation and Cholesterol-Rich Domains in the Plasma Membrane Facilitates T Cell Activation

Wang, Hongyin, Diaz-Rohrer, Barbara, Levental, Kandice R., Ditlev, Jonathon A., Rosen, Michael K., Levental, Ilya

Journal:

Biophysical Journal

Année:

2020

Fichier:

PDF, 47 KB

2020